Not really, network based system is scalable and the maximum number of devices can be increased by making the network larger. It depends mainly on how you set up your IP network and how many separate audio streams and other traffic you have on the network. A correctly configured network can support hundreds of Smart IP loudspeakers on the same network. 

See also:
What’s the maximum number of devices that an Ultimo-only network can support? (Audinate FAQ article)