How to setup 5.1 or 5.2 Genelec SAM-system for immersive movie playback (dolby/dts) and gaming both using PC as a platform?

If you want to use the PC or gaming console as a sound source, you would have to use the HDMI output and run this into an AV receiver that offers analog Pre-Outputs. There you can connect the Genelec speakers (can be RCA or XLR).